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ARAP3 antibody

CAT: 0710-FNab00523Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00523Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns (3,4,5) P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns (3,4,5) P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.
Synonyms
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3|Centaurin-delta-3 (Cnt-d3) |ARAP3|CENTD3
Gene ID
64411
UniProt
Q8WWN8
Host
Rabbit
Reactivity
Human
Immunogen
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Target
ARAP3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC

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