AQR antibody

CAT: 0710-FNab00520Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0710-FNab00520Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.

Synonyms

RNA helicase aquarius|Intron-binding protein of 160 kDa (IBP160) |AQR|KIAA0560

Gene ID

9716

UniProt

O60306

Host

Rabbit

Reactivity

Human

Immunogen

Aquarius homolog (Mouse)

Target

AQR

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Neuroscience

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

160 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

UniProtKB · O60306

RNA helicase aquarius

AQR_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: O60306
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: AQR
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 3.6.4.13
Processing: —
Secondary accessions: A0JP17, A5YKK3, Q2YDX9, Q6IRU8, Q6PIC8

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

Acetylation

Ligand

ATP-bindingNucleotide-binding

Molecular function

HelicaseHydrolaseRNA-binding

Biological process

mRNA processingmRNA splicing

Cellular component

NucleusSpliceosome

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