AP4M1 antibody

• Background:

  Component of the AP-4 complex, a novel type of clathrin-or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. Plays a role in the intracellular trafficking of APP from the trans-Golgi network (TGN) to endosomes, and thereby inhibits amyloidogenic processing of APP.

• Synonyms:

  AP-4 complex subunit mu-1|AP-4 adaptor complex mu subunit|Adaptor-related protein complex 4 subunit mu-1|Mu subunit of AP-4|Mu-adaptin-related protein 2 (mu-ARP2) |Mu4-adaptin (mu4) |AP4M1|MUARP2

• Gene ID:

  9179

• UniProt:

  O00189

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Adaptor-related protein complex 4, mu 1 subunit

• Target:

  AP4M1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC, WB

• Field of Research:

  Signal Transduction, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  50-55 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IHC, WB