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AP3B2 antibody

CAT: 0710-FNab00464Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab00464Size:100 µg
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Background
Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Synonyms
AP-3 complex subunit beta-2|Adaptor protein complex AP-3 subunit beta-2|Adaptor-related protein complex 3 subunit beta-2|Beta-3B-adaptin|Clathrin assembly protein complex 3 beta-2 large chain|Neuron-specific vesicle coat protein beta-NAP|AP3B2
Gene ID
8120
UniProt
Q13367
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Adaptor-related protein complex 3, beta 2 subunit
Target
AP3B2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB,IP
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000 IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
120-140 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP

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