AP3B1 antibody

• Background:

  Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

• Synonyms:

  AP-3 complex subunit beta-1|Adaptor protein complex AP-3 subunit beta-1|Adaptor-related protein complex 3 subunit beta-1|Beta-3A-adaptin|Clathrin assembly protein complex 3 beta-1 large chain|AP3B1|ADTB3A

• Gene ID:

  8546

• UniProt:

  O00203

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Adaptor-related protein complex 3, beta 1 subunit

• Target:

  AP3B1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IF, IP

• Field of Research:

  Signal Transduction, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:5000 IP: 1:200-1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  140 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IF, IP