AFAP1 antibody

• Background:

  Can cross-link actin filaments into both network and bundle structures (By similarity) . May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.

• Synonyms:

  Actin filament-associated protein 1|110 kDa actin filament-associated protein (AFAP-110) |AFAP1|AFAP

• Gene ID:

  60312

• UniProt:

  Q8N556

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Actin filament associated protein 1

• Target:

  AFAP1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IF

• Field of Research:

  Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:5000; IF: 1:10-1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  81 kDa, 110 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IF