AFDN antibody

• Background :

  MLLT4, also named as AF6 and Afadin, belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs) . It is a nNectin-and actin-filament-binding protein that connects nectin to the actin cytoskeleton. The antibody is specific to MLLT4.

• Synonyms :

  Afadin|ALL1-fused gene from chromosome 6 protein (Protein AF-6) |Afadin adherens junction formation factor|AFDN|AF6|MLLT4

• Gene ID :

  4301

• UniProt :

  P55196

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) ; translocated to, 4

• Target :

  AFDN

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB

• Field of Research :

  Signal Transduction

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  207 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB