AFDN antibody

• Background:

  MLLT4, also named as AF6 and Afadin, belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs) . It is a nNectin-and actin-filament-binding protein that connects nectin to the actin cytoskeleton. The antibody is specific to MLLT4.

• Synonyms:

  Afadin|ALL1-fused gene from chromosome 6 protein (Protein AF-6) |Afadin adherens junction formation factor|AFDN|AF6|MLLT4

• Gene ID:

  4301

• UniProt:

  P55196

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) ; translocated to, 4

• Target:

  AFDN

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  207 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB