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ABCE1 antibody

CAT: 0710-FNab00039Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00039Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.
Synonyms
ATP-binding cassette sub-family E member 1|2'-5'-oligoadenylate-binding protein|HuHP68|RNase L inhibitor|Ribonuclease 4 inhibitor (RNS4I) |ABCE1|RLI|RNASEL1|RNASELI|RNS4I
Gene ID
6059
UniProt
P61221
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
ATP-binding cassette, sub-family E (OABP), member 1
Target
ABCE1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
67 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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