ABCE1 antibody

• Background:

  Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.

• Synonyms:

  ATP-binding cassette sub-family E member 1|2'-5'-oligoadenylate-binding protein|HuHP68|RNase L inhibitor|Ribonuclease 4 inhibitor (RNS4I) |ABCE1|RLI|RNASEL1|RNASELI|RNS4I

• Gene ID:

  6059

• UniProt:

  P61221

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  ATP-binding cassette, sub-family E (OABP), member 1

• Target:

  ABCE1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  67 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB