ABCB1 antibody

CAT: 0710-FNab09805Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab09805Size:100 µg
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AVAILABILITY: InStock
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Background
ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.
Synonyms
ATP-dependent translocase ABCB1|ATP-binding cassette sub-family B member 1|Multidrug resistance protein 1|P-glycoprotein 1|Phospholipid transporter ABCB1|ABCB1|MDR1|PGY1
Gene ID
5243
UniProt
P08183
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
ABCB1
Target
ABCB1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP, IHC
Field of Research
Neuroscience, Immunology, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
142 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP, IHC

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