ABCB1 antibody

• Background:

  ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.

• Synonyms:

  ATP-dependent translocase ABCB1|ATP-binding cassette sub-family B member 1|Multidrug resistance protein 1|P-glycoprotein 1|Phospholipid transporter ABCB1|ABCB1|MDR1|PGY1

• Gene ID:

  5243

• UniProt:

  P08183

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  ABCB1

• Target:

  ABCB1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IP, IHC

• Field of Research:

  Neuroscience, Immunology, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:500

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  142 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IP, IHC