Fmoc-PEA

• Description :

  Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC) [1].

• UNSPSC :

  12352203

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  ADC Linker

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/fmoc-pea.html

• Purity :

  99.47

• Solubility :

  DMSO : 200 mg/mL (ultrasonic)

• Smiles :

  O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOP(O)(O)=O

• Molecular Formula :

  C17H18NO6P

• Molecular Weight :

  363.30

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]GARBACCIO, Robert, M., et al. PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES. WO2015153401A1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• Isoform :

  Cleavable Linker; Phosphatase Cleavable Linker

• CAS Number :

  [329223-23-6]