RIPK-IN-4

RIPK-IN-4

• CAS Number: 2141969-56-2
• UNSPSC Description: RIPK-IN-4 is a potent and selective RIPK2 inhibitor with excellent oral bioavailability, and has an IC50 of 3 nM[1].
• Target Antigen: RIP kinase
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/ripk-in-4.html
• Purity: 99.71
• Solubility: DMSO : 31.25 mg/mL (ultrasonic)
• Smiles: O=S(C1=CN2C(C3=CC(N)=NC(F)=C3)=CN=C2C=C1OCC)(C(C)(C)C)=O
• Molecular Weight: 392.45
• References & Citations: [1]He X, et al. Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. ACS Med Chem Lett. 2017 Sep 27;8(10):1048-1053.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported