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AZD6564

CAT: 0804-HY-12586Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-12586Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD6564 is an orally active inhibitor for fibrinolysis through disruption of plasma kinase-fibrin interaction. AZD6564 dissolves human plasma clot with an IC50 of 0.44 μM. AZD6564 ameliorates hemorrhage in rats with EC50 of 1.62 μM, and exhibits good pharmacokinetic characteristics in rats[1].
CAS Number
[1251841-50-5]
UNSPSC
12352005
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/azd6564.html
Smiles
CC(C)(C)C[C@@H]1NCC[C@H](C(ON2)=CC2=O)C1
Molecular Formula
C13H22N2O2
Molecular Weight
238.33
References & Citations
[1]Cheng L, et al., Discovery of the Fibrinolysis Inhibitor AZD6564, Acting via Interference of a Protein-Protein Interaction. ACS Med Chem Lett. 2014 Feb 18;5 (5) :538-43.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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