3′-O-Methyladenosine

3′-O-Methyladenosine

• CAS Number: 10300-22-8
• UNSPSC Description: (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol (Adenosine, 3'-O-methyl- (8CI)(9CI)) is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/3-o-methyladenosine.html
• Purity: 97.0
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O[C@@H]1[C@H](OC)[C@@H](CO)O[C@H]1N2C=NC3=C(N=CN=C32)N
• Molecular Weight: 281.272
• References & Citations: [1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported