AHR antagonist 5 (free base)

AHR antagonist 5 (free base)

• CAS Number: 2247950-42-9
• UNSPSC Description: AHR antagonist 5 free base is a selective and orally active aryl hydrocarbon receptor (AHR) inhibitor. AHR antagonist 5 free base effectively blocks AHR from translocating from the cytoplasm to the nucleus. AHR antagonist 5 free base is highly selective for AHR over other receptors, transporters, and kinases[1].
• Target Antigen: Aryl Hydrocarbon Receptor
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/ahr-antagonist-5-free-base.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: CC(C)C(C=N1)=C2N1C(N[C@H]3CC4=C(CC3)NC5=CC=CC=C45)=NC(C6=CN=CC(F)=C6)=N2
• Molecular Weight: 441.50
• References & Citations: [1]Marta Sanchez-Martin, et al. Ahr inhibitors and uses thereof. WO2021142180A1.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported