TOFA-Plasmalogen

• UNSPSC Description:

  TOFA-Plasmalogen (compound 1) is a glyceraldehyde derivative with ferroptosis-inducing activity. TOFA-Plasmalogen causes cytotoxicity by promoting lipid peroxidation on cell membranes (IC50=32.87 μM)[1].

• Target Antigen:

  Ferroptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/tofa-plasmalogen.html

• Smiles:

  C[N+](C)(C)CCOP(OC[C@H](OC(CC/C=C/C=C)=O)CO/C=C\CCCCCCCCCCCCCCCC)([O-])=O

• Molecular Weight:

  615.82

• References & Citations:

  [1]Qiliang Zhang, et al. "Synthesis of Plasmalogen Derivatives with Unnatural Fatty Acids as Substrates for Ferroptosis Induction." ACS Chemical Biology (2024).

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported