TOFA-Plasmalogen

CAT:

804-HY-161947

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UNSPSC Description: TOFA-Plasmalogen (compound 1) is a glyceraldehyde derivative with ferroptosis-inducing activity. TOFA-Plasmalogen causes cytotoxicity by promoting lipid peroxidation on cell membranes (IC50=32.87 μM)[1].
Target Antigen: Ferroptosis
Type: Reference compound
Related Pathways: Apoptosis
Field of Research: Others
Assay Protocol: https://www.medchemexpress.com/tofa-plasmalogen.html
Smiles: C[N+](C)(C)CCOP(OC[C@H](OC(CC/C=C/C=C)=O)CO/C=C\CCCCCCCCCCCCCCCC)([O-])=O
Molecular Weight: 615.82
References & Citations: [1]Qiliang Zhang, et al. "Synthesis of Plasmalogen Derivatives with Unnatural Fatty Acids as Substrates for Ferroptosis Induction." ACS Chemical Biology (2024).
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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