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BM152054

CAT: 0804-HY-U00259-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-U00259-02Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BM152054 is a potent PPARgamma-activator. BM152054 can promote glucose utilization in peripheral tissues by enhancing insulin action[1][2].
CAS Number
213411-84-8
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/BM152054.html
Solubility
10 mM in DMSO
Smiles
O=C(N1)SC(CC2=C3C(C=CS3)=C(OCCC4=C(C)OC(C5=CC=CS5)=N4)C=C2)C1=O
Molecular Formula
C22H18N2O4S3
Molecular Weight
470.58
References & Citations
[1]Yoel Kloog, et al. Ras inhibitors for treating diseases or pathological conditions characterized insulin resistance. WO 2012104846 A1|[2]Fürnsinn C, et al. Chronic and acute effects of thiazolidinediones BM13.1258 and BM15.2054 on rat skeletal muscle glucose metabolism. Br J Pharmacol. 1999;128 (6) :1141-1148.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

5-[[4-[2-(5-Methyl-2-thiophen-2-yl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl]methyl]-1,3-thiazolidine-2,4-dione
CAS Number213411-84-8
PubChem CID9912581
IUPAC Name5-[[4-[2-(5-methyl-2-thiophen-2-yl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl]methyl]-1,3-thiazolidine-2,4-dione
Molecular FormulaC22H18N2O4S3
Molecular Weight470.6
XLogP5.2
Topological Polar Surface Area163
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Heavy Atom Count31
Formal Charge0
Complexity683
SMILES
CC1=C(N=C(O1)C2=CC=CS2)CCOC3=C4C=CSC4=C(C=C3)CC5C(=O)NC(=O)S5
InChI
InChI=1S/C22H18N2O4S3/c1-12-15(23-21(28-12)17-3-2-9-29-17)6-8-27-16-5-4-13(19-14(16)7-10-30-19)11-18-20(25)24-22(26)31-18/h2-5,7,9-10,18H,6,8,11H2,1H3,(H,24,25,26)
InChIKey
MZRQLASUMBMPRS-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 5-[[4-[2-(5-Methyl-2-thiophen-2-yl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl]methyl]-1,3-thiazolidine-2,4-dione
CAS: 213411-84-8
CID: 9912581
Formula: C22H18N2O4S3
MW: 470.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight470.6
XLogP35.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass470.04287058
Monoisotopic Mass470.04287058
Topological Polar Surface Area163 Ų
Heavy Atom Count31
Formal Charge0
Complexity683
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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CatalogName
T19211-01BM152054

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