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WD2000-012547

CAT: 0804-HY-U00223Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-U00223Size:1 Each
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Description
WD2000-012547 is a selective poly (ADP-ribose) -polymerase (PARP-1) inhibitor with a pKi of 8.221.
CAS Number
283172-68-9
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/WD2000-012547.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC1)C2=CC=CC3=C2C1=C(C4=CC=CC=C4)N3
Molecular Formula
C17H14N2O
Molecular Weight
262.31
References & Citations
[1]Fatima S, et al. Multiple receptor conformation docking, dock pose clustering and 3D QSAR studies on human poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors. J Recept Signal Transduct Res. 2014 Oct;34 (5) :417-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP1

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