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ZSET-845

CAT: 0804-HY-U00114Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-U00114Size:1 Each
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Description
ZSET-845 is a cognitive enhancer which enhances choline acetyltransferase activity in the hippocampus in the rat.
CAS Number
324077-62-5
UNSPSC
12352005
Target
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ZSET-845.html
Solubility
10 mM in DMSO
Smiles
O=C1N=C2C=CC=CN2C1(CC3=CC=CC=C3)CC4=CC=CC=C4
Molecular Formula
C21H18N2O
Molecular Weight
314.38
References & Citations
[1]Yamaguchi Y, et al. Ameliorative effects of azaindolizinone derivative ZSET845 on scopolamine-induced deficits in passive avoidance and radial-arm maze learning in the rat. Jpn J Pharmacol. 2001 Nov;87 (3) :240-4.|[2]Yamaguchi Y, et al. Antiamnesic effects of azaindolizinone derivative ZSET845 on impaired learning and decreased ChAT activity induced by amyloid-beta 25-35 in the rat. Brain Res. 2002 Aug 2;945 (2) :259-65.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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