Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA)
CAT:
804-HY-P1613A
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA)
- CAS Number: 199807-33-5
- UNSPSC Description: Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) (Cyclo(RGDfV) (TFA))is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) can be used for the research of acute myeloid leukemia[1].
- Target Antigen: Apoptosis; Integrin
- Type: Peptides
- Related Pathways: Apoptosis;Cytoskeleton
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/Cyclo_Arg-Gly-Asp-D-Phe-Val__TFA.html
- Purity: 99.77
- Solubility: 10 mM in DMSO|H2O : 2 mg/mL (ultrasonic;warming;adjust pH to 2-3 with HCl)
- Smiles: O=C([C@@H](NC(CNC([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC1=O)=O)=O)=O)CC(O)=O)N[C@@H]1CC2=CC=CC=C2.FC(C(O)=O)(F)F
- Molecular Weight: 688.65
- References & Citations: [1]Shen ZH, et al. Targeting of the leukemia microenvironment by c(RGDfV) overcomes the resistance to chemotherapy in acute myeloid leukemia in biomimetic polystyrene scaffolds. Oncol Lett. 2016 Nov;12(5):3278-3284.
- Shipping Conditions: Blue Ice
- Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported