Cyclo(Arg-Gly-Asp-D-Phe-Val)

CAT:

804-HY-P1613

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CAS Number: 137813-35-5
UNSPSC Description: Cyclo(Arg-Gly-Asp-D-Phe-Val) (Cyclo(RGDfV)) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) can be used for the research of acute myeloid leukemia[1].
Target Antigen: Apoptosis; Integrin
Type: Peptides
Related Pathways: Apoptosis;Cytoskeleton
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/cyclo-arg-gly-asp-d-phe-val.html
Solubility: 10 mM in DMSO
Smiles: O=C([C@@H](NC(CNC([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC1=O)=O)=O)=O)CC(O)=O)N[C@@H]1CC2=CC=CC=C2
Molecular Weight: 574.63
References & Citations: [1]Shen ZH, et al. Targeting of the leukemia microenvironment by c(RGDfV) overcomes the resistance to chemotherapy in acute myeloid leukemia in biomimetic polystyrene scaffolds. Oncol Lett. 2016 Nov;12(5):3278-3284.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-P1613	Cyclo(Arg-Gly-Asp-D-Phe-Val)
HY-P1613A	Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA)
HY-P2300-02	Cyclo(Arg-Gly-Asp-D-Phe-Cys)
HY-P2300-01	Cyclo(Arg-Gly-Asp-D-Phe-Cys)
HY-P2300-04	Cyclo(Arg-Gly-Asp-D-Phe-Cys)
HY-P5021-02	Cyclo(Arg-Gly-Asp-(D-Phe)-Glu)
HY-P5021-01	Cyclo(Arg-Gly-Asp-(D-Phe)-Glu)
HY-P2300-03	Cyclo(Arg-Gly-Asp-D-Phe-Cys)
HY-P2300A-02	Cyclo(Arg-Gly-Asp-D-Phe-Cys) (TFA)
HY-P10303-01	Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)]