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β-Amyloid (12-28)

CAT: 0804-HY-P1051Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P1051Size:1 Each
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Description
β-Amyloid (12-28) (Amyloid β-Protein (12-28) ) is a peptide fragment of β-amyloid protein (β1-42) . β1-42, a 42 amino acid protein , is the major component of senile plaque cores. β-Amyloid (12-28) shows aggregation properties. β-Amyloid (12-28) has the potential for Alzheimer’s disease research[1].
CAS Number
107015-83-8
Product Name Alternative
Amyloid β-Protein (12-28)
UNSPSC
12352209
Target
Amyloid-β
Type
Peptides
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/_beta_-amyloid_12-28.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CC2=CNC=N2)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N
Molecular Formula
C89H135N25O25
Molecular Weight
1955.18
References & Citations
[1]Rabanal F, et al. Structural, kinetic and cytotoxicity aspects of 12-28 beta-amyloid protein fragment: a reappraisal. J Pept Sci. 2002 Oct;8 (10) :578-88.|[2]Nikunj S Patel, et al. Potent anti-angiogenic motifs within the Alzheimer beta-amyloid peptide. Amyloid. 2008 Mar;15 (1) :5-19.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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