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Schinifoline

CAT: 0804-HY-N4164-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N4164-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Schinifoline is a 4-quinolinone found in Zanthoxylum schinifolium. Schinifoline can inhibit cancer cells proliferation, cause G2/M phase arrest and induce apoptosis. Schinifoline can improve radiosensitizing effect of cancer cells. Schinifoline shows anti-fungal activity. Schinifoline can be used for the researches of cancer and infection, such as lung cancer and C. albicans infection[1][2].
CAS Number
80554-58-1
UNSPSC
12352005
Hazard Statement
H300, H315, H319, H335
Target
Apoptosis; Fungal
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/schinifoline.html
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=C(CCCCCCC)N(C)C2=C1C=CC=C2
Molecular Formula
C17H23NO
Molecular Weight
257.37
Precautions
H300, H315, H319, H335
References & Citations
[1]Wang CF, et al. Radiosensitizing effect of schinifoline from Zanthoxylum schinifolium Sieb et Zucc on human non-small cell lung cancer A549 cells: a preliminary in vitro investigation. Molecules. 2014 Dec 1;19 (12) :20128-38.|[2]Lu L, et al. Whole transcriptome analysis of schinifoline treatment in Caenorhabditis elegans infected with Candida albicans. Mol Immunol. 2021 Jul;135:312-319.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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