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MTNR1B Antibody

CAT: 0013-GTR18126571Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18126571Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MTNR1B Antibody
Product Name Alternative
MTNR1B, melatonin receptor 1B, MEL-1B-R, MT2, melatonin receptor MEL1B, melatonin receptor type 1B
UniProt
P49286
Reactivity
Human
Immunogen
The immunogen for this antibody is: C-QDASKGSHAEGLQSP
Target
MTNR1B
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Neuroscience, Signal Transduction
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
500 ug/mL
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments gave approx .48kDa and 37kDa bands in Human Brain (Cerebellum) lysates after 1μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 40.2kDa according to NP_005950.1. The 48kDa and 37kDa bands were successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?Immunohistochemistry:In paraffin embedded Human Cerebellum shows membranous staining primarily in Purkinje cells. Recommended concentration, 3-6μg/mL.
Tested Applications
ELISA, IHC
NCBI Accession Number
NP_005950.1
Host or Source
Goat
Preservative
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

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