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KCNQ3 Antibody

CAT: 0013-GTR18127512Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18127512Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KCNQ3 Antibody
Product Name Alternative
KCNQ3, potassium voltage-gated channel, KQT-like subfamily, member 3, BFNC2, EBN2, KV7.3, potassium channel, voltage-gated, subfamily Q, member 3, potassium voltage-gated channel KQT-like protein 3
UniProt
O43525
Immunogen
The immunogen for this antibody is: C-SDSVWTPSNKPI
Target
KCNQ3
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Neuroscience
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
500 ug/mL
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Peptide ELISA: antibody detection limit dilution 1:16000.Western Blot:Preliminary experiments gave an approx. 23kDa band in Human Brain (Cerebral Cortex, Amygdala, Hippocampus) lysates after 0.3μg/mL antibody staining. Please note that currently we can not find an explanation in the literature for the band we observe given the calculated size of 96.7kDa according to NP_004510.1. The 23kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Prediction Reactivity
Human, Mouse, Porcine, Rat
Tested Applications
ELISA
NCBI Accession Number
NP_004510.1
Host or Source
Goat
Preservative
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

UniProtKB · O43525

Potassium voltage-gated channel subfamily KQT member 3

KCNQ3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O43525
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KCNQ3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A2VCT8, B4DJY4, E7EQ89
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

Disease

Disease variantEpilepsy

Molecular function

Ion channelPotassium channelVoltage-gated channel

Biological process

Ion transportPotassium transportTransport

PTM

PhosphoproteinUbl conjugation

Ligand

Potassium

Domain

TransmembraneTransmembrane helix

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