Ibandronate (Sodium)

• UNSPSC Description:

  Ibandronate sodium is a highly active nitrogen-containing bisphosphonate that can be used for osteoporosis.

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ibandronate-sodium.html

• Solubility:

  10 mM in H2O

• Smiles:

  OC(P(O)(O)=O)(P(O)([O-])=O)CCN(C)CCCCC.[Na+]

• Molecular Weight:

  341.21

• References & Citations:

  [1]Morgan, C., S. Jeremiah, and J. Wagstaff, Metronomic administration of ibandronate and its anti-angiogenic effects in vitro. Microvasc Res, 2009. 78(3): p. 453-8.|[2]Epplen, R., et al., Differential effects of ibandronate, docetaxel and farnesol treatment alone and in combination on the growth of prostate cancer cell lines. Acta Oncol, 2011. 50(1): p. 127-33.|[3]Chesnut, I.C., et al., Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis. J Bone Miner Res, 2004. 19(8): p. 1241-9.|[4]Bauss, F., et al., Effects of treatment with ibandronate on bone mass, architecture, biomechanical properties, and bone concentration of ibandronate in ovariectomized aged rats. J Rheumatol, 2002. 29(10): p. 2200-8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Launched

• CAS Number:

  138844-81-2