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Felbamate (hydrate)

CAT: 0804-HY-B0184ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B0184ASize:1 Each
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Description
Felbamate hydrate (W-554 hydrate) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA) .
CAS Number
1177501-39-1
Product Name Alternative
W-554 (hydrate) ; ADD-03055 (hydrate)
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/felbamate-hydrate.html
Solubility
10 mM in DMSO
Smiles
NC(OCC(C1=CC=CC=C1)COC(N)=O)=O.O
Molecular Formula
C11H16N2O5
Molecular Weight
256.26
References & Citations
[1]Kuo CC, et al. Use-dependent inhibition of the N-methyl-D-aspartate currents by felbamate: a gating modifier with selective binding to the desensitized channels. Mol Pharmacol. 2004 Feb;65 (2) :370-80.|[2]Harty TP, et al. Felbamate block of recombinant N-methyl-D-aspartate receptors: selectivity for the NR2B subunit. Epilepsy Res. 2000 Mar;39 (1) :47-55.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
NMDA Receptor

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