GV-196771A

• UNSPSC Description:

  GV-196771A is the sodium salt form of GV196771, is an NMDA receptor antagonist.

• Target Antigen:

  iGluR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/GV-196771A.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C(N1)=C(/C=C2C(N(C3=CC=CC=C3)CC/2)=O)C4=C1C=C(Cl)C=C4Cl)[O-].[Na+]

• Molecular Weight:

  423.22

• References & Citations:

  [1]Polli JW, et al. The systemic exposure of an N-methyl-D-aspartate receptor antagonist is limited in mice by the P-glycoprotein and breast cancer resistance protein efflux transporters. Drug Metab Dispos. 2004 Jul;32(7):722-6.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  166974-23-8