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Levalbuterol (tartrate)

CAT: 0804-HY-17457Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-17457Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Levosalbutamol tartrate (levalbuterol) is the R-enantiomer of the short-acting β2-adrenergic receptor agonist salbutamol. IC50 Value: Target: β2-adrenergic receptor Levosalbutamol and salbutamol produced significantly better bronchodilator responses than placebo. Both the drugs showed equivalent time-dependent bronchodilator responses as measured by area under curve for percent change in FEV (1) and FVC over 6h. The time to onset of action, mean maximum bronchodilator response and duration of bronchodilator response were similar between levosalbutamol and salbutamol [1].
CAS Number
661464-94-4
Product Name Alternative
Levosalbutamol tartrate
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/levalbuterol-tartrate.html
Solubility
10 mM in DMSO
Smiles
OC1=C(CO)C=C([C@@H](O)CNC(C)(C)C)C=C1.OC2=C(CO)C=C([C@@H](O)CNC(C)(C)C)C=C2.OC([C@H](O)[C@@H](O)C(O)=O)=O
Molecular Formula
C30H48N2O12
Molecular Weight
628.71
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Jantikar A, et al. Comparison of bronchodilator responses of levosalbutamol and salbutamol given via a pressurized metered dose inhaler: a randomized, double blind, single-dose, crossover study. Respir Med. 2007 Apr;101 (4) :845-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor