Netupitant-d6

• Description :

  Netupitant-d6 is the deuterium labeled Netupitant (CID-6451149), which is a highly potent and selective, orally active neurokinin-1 (NK1) receptor antagonist[1].

• Product Name Alternative :

  CID-6451149-d6

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319

• Target :

  Neurokinin Receptor

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Endocrinology; Neurological Disease

• Purity :

  99.56

• Solubility :

  10 mM in DMSO|DMSO : 9.09mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  CN(CC1)CCN1C2=CC(C3=CC=CC=C3C)=C(N(C)C(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=O)C=N2

• Molecular Formula :

  C30H26D6F6N4O

• Molecular Weight :

  584.63

• Precautions :

  H315, H319

• References & Citations :

  [1]Hoffmann T, et al. Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonists. Bioorg Med Chem Lett. 2006 Mar 1;16 (5) :1362-5.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [2070015-31-3]