FTI 276

CAT: 0804-HY-15873Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-15873Size:1 Each
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Description
FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 and 0.5 nM for Plasmodium falciparum and human.
CAS Number
[170006-72-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Farnesyl Transferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/FTI_276.html
Solubility
10 mM in DMSO
Smiles
O=C(O)[C@@H](NC(C1=CC=C(NC[C@@H](N)CS)C=C1C2=CC=CC=C2)=O)CCSC
Molecular Formula
C21H27N3O3S2
Molecular Weight
433.59
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Chakrabarti D, et al. Protein farnesyltransferase and protein prenylation in Plasmodium falciparum.J Biol Chem. 2002 Nov 1; 277 (44) :42066-73. Epub 2002 Aug 22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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