Avermectin B1a (Standard)

Avermectin B1a (Standard)

• CAS Number: 65195-55-3
• UNSPSC Description: Avermectin B1a (Standard) is the analytical standard of Avermectin B1a. This product is intended for research and analytical applications. Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.
• Target Antigen: Antibiotic; Parasite
• Type: Reference Standards
• Related Pathways: Anti-infection
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/avermectin-b1a-standard.html
• Smiles: C[C@@H](CC)[C@]1([H])[C@@H](C)C=C[C@@]2(O[C@@]3([H])C[C@]([H])(OC([C@@]4([H])[C@@](/C(CO5)=C/C=C/[C@H](C)[C@H](O[C@@]6([H])C[C@H](OC)[C@@H](O[C@]7([H])O[C@@H](C)[C@H](O)[C@@H](OC)C7)[C@H](C)O6)/C(C)=C/C3)(O)[C@@]5([H])[C@H](O)C(C)=C4)=O)C2)O1
• Molecular Weight: 873.08
• References & Citations: [1]Sun Y, et al. [Effects of avermectin B1a on soil microorganism and earthworm (Eisenia fetida)]. Ying Yong Sheng Tai Xue Bao. 2005 Nov;16(11):2140-3.|[2]Sun Y, et al. Bioaccumulation and elimination of avermectin B1a in the earthworms (Eisenia fetida). Chemosphere. 2005 Jul;60(5):699-704|[3]Huang J, et al. Avermectin B1a binds to high- and low-affinity sites with dual effects on the gamma-aminobutyric acid-gated chloride channel of cultured cerebellar granule neurons. J Pharmacol Exp Ther. 1997 Apr;281(1):261-6.|[4]Payne GT, et al. Activation of gamma-aminobutyric acid insensitive chloride channels in mouse brain synaptic vesicles by avermectin B1a.
 J Biochem Toxicol. 1991 Winter;6(4):283-92.
• Shipping Conditions: Room temperature