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1-Methyladenine

CAT: 0804-HY-113306Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113306Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
1-Methyladenine is a product of alkylation damage in DNA which can be repaired by damage reversal by oxidative demethylation.
CAS Number
5142-22-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/1-Methyladenine.html
Purity
99.99
Solubility
DMSO : 5 mg/mL (ultrasonic) |H2O : 4.72 mg/mL (ultrasonic; warming; adjust pH to 3 with 1 M HCl; heat to 60°C)
Smiles
NC1=C2N=CN=C2N=CN1C
Molecular Formula
C6H7N5
Molecular Weight
149.15
Precautions
H302, H315, H319, H335
References & Citations
[1]Falnes PØ, et al. Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins. Nucleic Acids Res. 2004 Dec 1;32 (21) :6260-7. Print 2004.|[2]Yang H, et al. Effect of 1-methyladenine on double-helical DNA structures. FEBS Lett. 2008 May 14;582 (11) :1629-33.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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