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JV-1-36

CAT: 0804-HY-P3397Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P3397Size:1 Each
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Description
JV-1-36 is a growth hormone-releasing hormone (GHRH) antagonist. JV-1-36 inhibits the production of reactive oxygen species in A549 lung cancer cells. JV-1-36 can be used to study the effect of GHRH antagonists in vitro [1].
CAS Number
221377-79-3
UNSPSC
12352209
Target
GHSR
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jv-1-36.html
Solubility
10 mM in DMSO
Smiles
N=C(NCCC[C@@H](NC([C@@H](NC(CC1=CC=CC=C1)=O)CC2=CC=C(C=C2)O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N)=O)CCCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCC)=O)[C@H](CC)C)=O)CC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CC(C)C)=O)CCCCN)=O)CCCNC(N)=N)=O)C)=O)CO)=O)CC(C)C)=O)CCC(N)=O)=O)CC)=O)CC(C)C)=O)C(C)C)=O)CCCCN)=O)CCCNC(N)=N)=O)CC3=CC=C(OC)C=C3)=O)CCCCNC(N)=N)=O)CC(N)=O)=O)[C@@H](C)O)=O)CC4=CC=C(Cl)C=C4)=O)[C@H](CC)C)=O)C)=O)CC(O)=O)=O)N
Molecular Formula
C172H284ClN53O41
Molecular Weight
3785.88
References & Citations
[1]Kubra KT, et al. Growth Hormone-Releasing Hormone Antagonist JV-1-36 Suppresses Reactive Oxygen Species Generation in A549 Lung Cancer Cells. Endocrines. 2022 Dec;3 (4) :813-820.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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