Ralfinamide (mesylate)

CAT: 0804-HY-101437A-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-101437A-01Size:5 mg
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Description
Ralfinamide mesylate (FCE-26742A mesylate) is an orally available Na+ channel blocker derived from α-aminoamide, with function of suppressing pain[1][2].
CAS Number
[202825-45-4]
Product Name Alternative
FCE-26742A (mesylate)
UNSPSC
12352005
Hazard Statement
H301
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ralfinamide-mesylate.html
Solubility
10 mM in DMSO
Smiles
C[C@H](NCC1=CC=C(OCC2=CC=CC=C2F)C=C1)C(N)=O.CS(=O)(O)=O
Molecular Formula
C18H23FN2O5S
Molecular Weight
398.45
Precautions
P264-P270-P330-P405-P501
References & Citations
[1]Zhang SH, et al. Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat. Pain. 2008 Oct 15;139 (2) :293-305.|[2]Liang X, et al. Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain. Eur J Pharmacol. 2018 Mar 15;823:27-34.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3

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