Ralfinamide

• Description :

  Ralfinamide (FCE-26742A) is an orally available Na+ blocker derived from α-aminoamide, with function of suppressing pain[1][2].

• Product Name Alternative :

  FCE-26742A

• UNSPSC :

  12352005

• Hazard Statement :

  H301

• Target :

  Sodium Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/ralfinamide.html

• Purity :

  99.78

• Solubility :

  DMSO : ≥ 125 mg/mL

• Smiles :

  C[C@H](NCC1=CC=C(OCC2=CC=CC=C2F)C=C1)C(N)=O

• Molecular Formula :

  C17H19FN2O2

• Molecular Weight :

  302.35

• Precautions :

  H301

• References & Citations :

  [1]Zhang SH, et al. Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat. Pain. 2008 Oct 15;139 (2) :293-305.|[2]Liang X, et al. Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain. Eur J Pharmacol. 2018 Mar 15;823:27-34.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 3

• CAS Number :

  [133865-88-0]