Y-26763

• Description :

  Y-26763 is a K+ channel opener and active metabolite of Y-27152[1]. Y-26763 is an ATP-sensitive K+ (KATP) channel activator[2].

• UNSPSC :

  12352005

• Target :

  Potassium Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/y-26763.html

• Purity :

  99.7

• Solubility :

  27 mg/mL (ultrasonic; warming)

• Smiles :

  CC(N([C@H]1[C@H](O)C(C)(C)OC2=CC=C(C#N)C=C12)O)=O

• Molecular Formula :

  C14H16N2O4

• Molecular Weight :

  276.29

• References & Citations :

  [1]Itoh T, et al. Effects of a newly synthesized K+ channel opener, Y-26763, on noradrenaline-induced Ca2+ mobilization in smooth muscle of the rabbit mesenteric artery. Br J Pharmacol. 1994 Jan;111 (1) :165-72.|[2]Tran QTN, et al. The identification of naturally occurring labdane diterpenoid calcaratarin D as a potential anti-inflammatory agent. Eur J Med Chem. 2019 Jul 15;174:33-44.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [127408-31-5]