Y-99

CAT: 0804-HY-176488Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-176488Size:1 Each

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Description

Y-99 is a PORCN inhibitor with an IC50 of 155.4 nM against the Wnt/β-catenin signaling pathway. Y-99 inhibits the expression of p-LRP6, β-catenin, and c-Myc[1].

CAS Number

2034334-74-0

UNSPSC

12352005

Target

C-Myc; Porcupine; Wnt; β-catenin

Related Pathways

Apoptosis; Stem Cell/Wnt

Field of Research

Cancer

Smiles

O=C(NCC1=NC(C2CCC(F)(F)CC2)=NO1)C3=NOC(C4=CC=CN=C4)=C3

Molecular Formula

C18H17F2N5O3

Molecular Weight

389.36

References & Citations

[1]Yang X, et al. Discovery and Identification of a Novel PORCN Inhibitor via Structure-Based Virtual Screening. ACS Chem Biol. 2025 Jun 20;20 (6) :1319-1332.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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Y-99

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