Roflumilast Impurity E

• Description:

  Roflumilast Impurity E is the impurity of Roflumilast. Roflumilast (Daliresp) is a agent which acts as a selective and long-acting inhibitor of the enzyme PDE-4 with an IC50 value of 0.8 nM.

• UNSPSC:

  12352005

• Hazard Statement:

  H315-H319-H335

• Target:

  Phosphodiesterase (PDE)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/Roflumilast-Impurity-E.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=C(Cl)C=NC=C1Cl)C2=CC=C(OC(F)F)C(O)=C2

• Molecular Formula:

  C13H8Cl2F2N2O3

• Molecular Weight:

  349.12

• Precautions:

  P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1391052-76-8