Mouse IL-34 Recombinant Protein

• Description:

  Interleukin-34 (IL-34) is a homodimeric cytokine recognized by colony-stimulating factor 1 receptor (CSF-1R) . IL-34 is involved in the survival, proliferation, and differentiation of mononuclear phagocytes. Mouse IL-34 Recombinant Protein is purified interleukin-15 produced in yeast.

• Synonyms:

  Interleukin-34; IL-34; Il34

• Gene Name:

  IL34

• UniProt:

  Q8R1R4

• Source:

  Yeast

• Sequence:

  [object Object]

• Applications:

  Cell Culture

• Field of Research:

  Cytokines, Immunology, Innate Immunity, Interleukins, Macrophage/Inflammation

• Purification:

  Ion-exchange chromatography.

• Bioactivity:

  In testing.

• Form:

  Lyophilized

• Function:

  Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1 (By similarity) .

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

• Subcellular Location:

  Secreted.