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Mouse APRIL Recombinant Protein

CAT: 0519-R02417-2Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0519-R02417-2Size:5 µg
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Description
A proliferation-inducing ligand (APRIL), also known as TNFSF13, is a member of the tumor necrosis factor (TNF) ligand superfamily. APRIL/TNFSF13 has been shown to play a role in protecting cells from undergoing apoptosis and promoting B cell development. Mouse APRIL Recombinant Protein is purified APRIL (TNFSF13) produced in yeast.
Synonyms
Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; CD256; Tnfsf13; April
Gene Name
TNFSF13
UniProt
Q9D777
Source
Yeast
Sequence
[object Object]
Applications
Cell Culture
Field of Research
Adaptive Immunity, B Cells, Cancer, Cytokines, Growth Factors, Growth Factors/Hormones, Immunology, Innate Immunity, Non-CD, Signal Transduction, TNF Superfamily
Purification
Ion-exchange chromatography.
Bioactivity
In testing.
Form
Lyophilized
Function
Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Subcellular Location
Secreted.

UniProtKB · Q9D777

Tumor necrosis factor ligand superfamily member 13

TNF13_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q9D777
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Tnfsf13
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q9ERP1
Protein keywords

Technical term

3D-structureReference proteome

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoprotein

Molecular function

Cytokine

Biological process

Immunity

Cellular component

Secreted