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BeKm-1

CAT: 0804-HY-P1440-01Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-P1440-01Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BeKm-1 is a HERG (human ether-a-go-go-related gene) blocking compound. BeKm-1 can be used for the research of heart disease[1].
CAS Number
524962-01-4
UNSPSC
12352209
Target
Potassium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bekm-1.html
Purity
99.51
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H](CSSC[C@@H](C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(NCC(N[C@H]2CC3=CC=CC=C3)=O)=O)=O)=O)NC4=O)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CSSC[C@@H](C(N[C@H]6CC(O)=O)=O)NC2=O)C(N[C@@H](CC7=CC=CC=C7)C(N8[C@@H](CCC8)C(N[C@@H](C(C)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC9=CC=CC=C9)C(O)=O)=O)NC6=O)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC%10=CC=CC=C%10)C(NCC(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(N)=O)C(NCC(N[C@H]4CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N
Molecular Formula
C174H261N51O52S6
Molecular Weight
4091.65
References & Citations
[1]Milnes JT, et al. Preferential closed channel blockade of HERG potassium currents by chemically synthesised BeKm-1 scorpion toxin. FEBS Lett. 2003;547 (1-3) :20-26.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported

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