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Avobenzone (Standard)

CAT: 0804-HY-B0316R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0316R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Avobenzone (Standard) is the analytical standard of Avobenzone. This product is intended for research and analytical applications. Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist[1][2].
CAS Number
70356-09-1
UNSPSC
12352005
Target
Apoptosis; Estrogen Receptor/ERR; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Others; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/avobenzone-standard.html
Purity
98.55
Smiles
O=C(C1=CC=C(C(C)(C)C)C=C1)CC(C2=CC=C(OC)C=C2)=O
Molecular Formula
C20H22O3
Molecular Weight
310.39
References & Citations
[1]Kojić M, et al. A new insight into the photochemistry of avobenzone in gas phase and acetonitrile from ab initio calculations. Phys Chem Chem Phys. 2016;18 (32) :22168-22178.|[2]Ahn S, An S, et al. A long-wave UVA filter avobenzone induces obesogenic phenotypes in normal human epidermal keratinocytes and mesenchymal stem cells. Arch Toxicol. 2019;93 (7) :1903-1915.|[3]Yang C, et al. Avobenzone suppresses proliferative activity of human trophoblast cells and induces apoptosis mediated by mitochondrial disruption. Reprod Toxicol. 2018;81:50-57.|[4]Schreurs RH, et al. Interaction of polycyclic musks and UV filters with the estrogen receptor (ER), androgen receptor (AR), and progesterone receptor (PR) in reporter gene bioassays. Toxicol Sci. 2005;83 (2) :264-272.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

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