STAT5A (Phospho-Ser780) Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC2517Size: 1 Kit, Containing two 96 Well Plates and all necessary reagentsDry Ice: NoHazardous: No

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CAT#:0519-EKC2517Size:1 Kit, Containing two 96 Well Plates and all necessary reagents

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

The STAT5A (Phospho-Ser780) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor STAT5A (Phospho-Ser780) protein expression profile in cells. The kit can be used for measuring the relative amounts of STAT5A (Phospho-Ser780) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on STAT5A (Phospho-Ser780) .

Synonyms

Signal transducer and activator of transcription 5A; STAT5A; STAT5

Gene Name

STAT5A

UniProt

P42229

Reactivity

Human, Mouse, Rat

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.

Molecular Weight

90647 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Signal transducer and activator of transcription 5A

Subcellular Location

Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.

UniProtKB · P42229

Signal transducer and activator of transcription 5A

STA5A_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P42229
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: STAT5A
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: Q1KLZ6

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Biological process

LactationTranscriptionTranscription regulation

PTM

PhosphoproteinUbl conjugation

Domain

SH2 domain

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