STAT5A/B (Phospho-Ser725/730) Colorimetric Cell-Based ELISA Kit

• Description:

  The STAT5A/B (Phospho-Ser725/730) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor STAT5A/B (Phospho-Ser725/730) protein expression profile in cells. The kit can be used for measuring the relative amounts of STAT5A/B (Phospho-Ser725/730) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on STAT5A/B (Phospho-Ser725/730) .

• Synonyms:

  MGF; MPF; Mammary gland factor; STA5A; STAT5; STAT5A; Signal transducer and activator of transcription 5A

• Gene Name:

  STAT5A

• UniProt:

  P42229

• Reactivity:

  Human, Mouse, Rat

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.

• Molecular Weight:

  90647 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Signal transducer and activator of transcription 5A

• Subcellular Location:

  Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.