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C-Jun (Phospho-Ser243) Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC2443Size: 1 Kit, Containing two 96 Well Plates and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC2443Size:1 Kit, Containing two 96 Well Plates and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The c-Jun (Phospho-Ser243) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor c-Jun (Phospho-Ser243) protein expression profile in cells. The kit can be used for measuring the relative amounts of c-Jun (Phospho-Ser243) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on c-Jun (Phospho-Ser243) .
Synonyms
Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39; JUN
Gene Name
JUN
UniProt
P05412
Reactivity
Human, Mouse, Rat
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306) . Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306) .
Molecular Weight
35676 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Transcription factor AP-1
Subcellular Location
Nucleus.

UniProtKB · P05412

Transcription factor Jun

JUN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05412
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
JUN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q6FHM7, Q96G93
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-binding

Cellular component

Nucleus

Disease

Proto-oncogene

Biological process

TranscriptionTranscription regulation

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