C-Jun Colorimetric Cell-Based ELISA Kit

• Description:

  The c-Jun Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor c-Jun protein expression profile in cells. The kit can be used for measuring the relative amounts of c-Jun in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on c-Jun.

• Synonyms:

  Activator protein 1; AH119; AP-1; AP1; c-Jun; Jun A; p39; Proto-oncogene c-jun; RJG-9; V-jun avian sarcoma virus 17 oncogene homolog

• Gene Name:

  JUN

• UniProt:

  P05412

• Reactivity:

  Human, Mouse, Rat

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306) . Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306) .

• Molecular Weight:

  35676 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Transcription factor AP-1

• Subcellular Location:

  Nucleus.