GATA1 (Phospho-Ser310) Colorimetric Cell-Based ELISA Kit

• Description:

  The GATA1 (Phospho-Ser310) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GATA1 (Phospho-Ser310) protein expression profile in cells. The kit can be used for measuring the relative amounts of GATA1 (Phospho-Ser310) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GATA1 (Phospho-Ser310) .

• Synonyms:

  Erythroid transcription factor; Eryf1; GATA-binding factor 1; GATA-1; GF-1; NF-E1 DNA-binding protein; GATA1; ERYF1, GF1

• Gene Name:

  GATA1

• UniProt:

  P15976

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Erythrocytes.

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed:24245781) .

• Molecular Weight:

  42751 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Erythroid transcription factor

• Subcellular Location:

  Nucleus.