Calmodulin (Phospho-Thr79+Ser81) Colorimetric Cell-Based ELISA Kit

• Description:

  The Calmodulin (Phospho-Thr79+Ser81) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Calmodulin (Phospho-Thr79+Ser81) protein expression profile in cells. The kit can be used for measuring the relative amounts of Calmodulin (Phospho-Thr79+Ser81) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Calmodulin (Phospho-Thr79+Ser81) .

• Synonyms:

  CALM; CALM1; CALM2; CALM3; CAM; CAM1; CAM2; CAM3; CAMB; CAMC

• Gene Name:

  CALM2 CAM2, CAMBCALM3 CALML2, CAM3, CAMC, CAMIIICALM1 CALM, CAM, CAM1

• UniProt:

  P62158

• Reactivity:

  Human, Mouse, Rat

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (PubMed:16760425) . Mediates calcium-dependent inactivation of CACNA1C (PubMed:26969752) . Positively regulates calcium-activated potassium channel activity of KCNN2 (PubMed:27165696) .

• Molecular Weight:

  16838 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Calmodulin-2

• Subcellular Location:

  Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.