ENOS Colorimetric Cell-Based ELISA

• Description:

  The eNOS Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor eNOS protein expression profile in cells. The kit can be used for measuring the relative amounts of eNOS in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on eNOS.

• Synonyms:

  Nitric oxide synthase, endothelial;1.14.13.39; Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; eNOS; N

• Gene Name:

  NOS3

• UniProt:

  P29474

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Platelets, placenta, liver and kidney.

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF) -induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

• Molecular Weight:

  133289 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Nitric oxide synthase, endothelial

• Subcellular Location:

  Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.