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MAP3KL4 Colorimetric Cell-Based ELISA

CAT: 0519-EKC1852Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1852Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The MAP3KL4 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MAP3KL4 protein expression profile in cells. The kit can be used for measuring the relative amounts of MAP3KL4 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MAP3KL4.
Synonyms
Mitogen-activated protein kinase kinase kinase 21;2.7.11.25; Mitogen-activated protein kinase kinase kinase MLK4; Mixed lineage kinase 4; MAP3K21 ; KIAA1804 , MLK4
Gene Name
MAP3K21 KIAA1804 , MLK4
UniProt
Q5TCX8
Reactivity
Human
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways.
Molecular Weight
113927 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Mitogen-activated protein kinase kinase kinase 21

UniProtKB · Q5TCX8

Mitogen-activated protein kinase kinase kinase 21

M3K21_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q5TCX8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MAP3K21
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.25
Processing
—
Secondary accessions
A0A1W2PKR9, B2RN34, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1, X6R610
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

Phosphoprotein

Domain

RepeatSH3 domain

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